ELN and keloid: Image analysis of immunohistochemical staining also revealed significantly reduced type I collagen, type III collagen, elastin, and fibronectin in dEl-RGD/GFP/shMot treated keloid spheroids, by 12%, 43%, 12%, and 18%, respectively, versus scramble virus-transduced spheroids (**p < 0.01 in all cases; Fig. 4b and c).