In addition, we also analyzed CCR6− Th cell subpopulations representing either Th2 (CCR6−CCR4+ CCR10−CXCR3−) or Th1 (CCR6−CCR4−CCR10−CXCR3+) profiles in SLE patients and HCs. This evidence concerns the gene CCR6 and systemic lupus erythematosus.