Similarly, we also did not find any significant correlation between plasma IFN-γ levels and the frequencies of Th1 or Th17.1 cells, or between plasma IL-17 levels and the frequencies of Th17 or Th17.1 cells, or plasma TNF-α level and the frequencies of different Th cell subsets in SLE patients. This evidence concerns the gene TNF and systemic lupus erythematosus.