HDAC6 and Charcot-Marie-Tooth disease type 2: In line with the rescue of axonal transport deficits in DRG neurons from a mouse model of CMT2 and in a Drosophila model of Parkinson disease23, 52, we believe that the therapeutic effect of HDAC6 inhibitors could be related to a more general effect due to the increase of the acetylation level of α-tubulin in the microtubules, rather than a (mutant) FUS-specific effect.