PHLDA1 and neoplasm: We discovered only seven genes (those encoding semaphorin 5A [SEMA5A], CXCL1, ENTPOT, follistatir [FST], cytochrome P450 [CYP] 24A1, pleckstrin homology-like domain A1 [PHLDA1], and ribosomal protein S27-like [RPS27L]) out of a total of 99 altered in another study using small interfering RNA (siRNA) depletion of E6 in HPV-positive tumor cells (47).