CCR4 and neoplasm: Svensson et al. analyzed seven different chemokine receptors in CRC patients in a similar fashion as we did and reported that the percentage of CXCR3+ cells among CD4+ and CD8+ T lymphocytes was lower in colorectal carcinoma tissue as compared with unaffected tissue, the percentage of CCR4+ cells was higher among tumor CD4+ but not CD8+ T lymphocytes, whereas five other chemokine receptors did not show any differences [44].