The overall average of the chemokine receptor expression frequencies showed that the T lymphocytes isolated from carcinoma tissues expressed lower levels of chemokine receptors (20.1 ± 5.6%) than those isolated from unaffected mucosa (26.9 ± 5.8%) (Wilcoxon test; p < 0.01) in CD4+ lymphocytes. This evidence concerns the gene CD4 and carcinoma.