UBE2I and Familial prostate cancer: But among 212 prostate cancer patients with high expression levels of KHSRP (median value >8732 FPKM, see in Table S1), the expression levels of Ubc9, which is only E2 conjugating enzyme for SUMOylation (Fig. 1a-b), was positively correlated with Gleason score (Pearson correlation with r value = 0.147*; P = 0.033).