The “Cardiovascular Outcomes in Participants with Type 2 Diabetes Mellitus” study, which compares CV outcomes of several drug classes (SGLT-2 inhibitors, GLP-1 RAs, DPP-4 inhibitors, Thiazolidinedione, Sulfonylureas and Insulin) could give further insight into this question. This evidence concerns the gene GLP1R and type 2 diabetes mellitus.