In the HFrEF group, SCD victims were less frequently under ARB or ACE inhibitors (p = 0.027) and were associated with higher ΔαTpe (p = 0.008) and TMR (p = 0.001) but lower TS (p = 0.025), while PFD victims were more frequently diabetic (p = 0.001), in NYHA class III (p = 0.001) and showed lower RR range (p = 0.003), ΔαTpe (p = 0.005) and TS values (p<0.001) but a higher rate of CIA (p = 0.030). Here, ACE is linked to Schnyder corneal dystrophy.