FYB1 and primary cutaneous T-cell non-Hodgkin lymphoma: Known upregulated targets in CTCL vs. benign dermatoses were validated, including TOX, FYB, LEF, and STAT signaling genes, inflammatory interleukins, NF-κB pathway signaling members, cancer testis genes, etc. We had previously reviewed in detail how these genes relate to the biology of CTCL tumorigenesis (3, 31).