MAPT and Alzheimer disease: Similar positive correlations were observed between p-tau and sAPPα and p-tau and sAPPβ among AD and MCI-AD groups (sAPPα: r = 0.434, p = 0.002; sAPPβ: r = 0.336, p = 0.017) and among other groups (sAPPα: r = 0.536, p = 0.0001; sAPPβ: r = 0.529, p = 0.0002), suggesting that differences in brain pathology do not considerably influence the association between p-tau and sAPPs.