Although PMN from some patients with PCD displayed increased migratory capacity in the Neuro Probe microchamber chemotaxis assay, overall PCD PMN showed reduced migration toward CXCL5 and CXCL8 (Figures 1A,B, respectively) compared to healthy PMN (p = 0.0011 and p = 0.0003, respectively), whereas migration toward LTB4 and C5a was not altered (Figures 1C,D, respectively). Here, C5AR1 is linked to primary ciliary dyskinesia.