CALCA and migraine disorder: Migraine patients have elevated levels of CGRP (Karsan and Goadsby, 2015; Edvinsson, 2017; Iyengar et al., 2017), the reduction of which has repeatedly been shown to constitute a promising treatment avenue (Olesen et al., 2004; Diener et al., 2015; Karsan and Goadsby, 2015; Mitsikostas and Rapoport, 2015).