After exposure to recent negative events, however, presence of the GABRA6 rs3219151 T allele increased risk of current depression (BSI-DEP) and anxiety (BSI-ANX), as well as specific elements of suicidal risk including directly suicide-related thoughts, hopelessness, restlessness and agitation, insomnia, and acute anxiety. The gene discussed is GABRA6; the disease is major depressive disorder.