Since two landmark genome-wide association studies (GWAS) performed on Japanese and Turkish populations [2, 3] identified HLA-A, IL10, and IL23R–IL12RB2 to be novel BD susceptibility loci, the association of IL10 and IL23R–IL12RB2 with BD has been replicated thereafter in various ethnic groups including the Chinese Han, Iranian, and Western Algerian populations [4–9]. This evidence concerns the gene IL12RB2 and Behcet disease.