IL12RB2 and Behcet disease: More importantly, association between BD risk and the IL23R–IL12RB2 locus was fine-mapped on the intergenic region rather than the IL23R or IL12RB2 gene, as the most significant association (P = 10−7) was observed with three almost perfectly correlated SNPs (r2 = 0.99), rs1495965, rs1495966, and rs4655535 located in the intergenic region, which may contain regulatory sequences for expression of IL23R, IL12RB2, or both.