On the other hand, binding matrixes enriched in AGO2 sites in both cell lines correspond to consensus motifs for NFATC2 and 5 and STAT4, all involved in BC development and metastasis [53–55], and for MEIS1 and SOX10, the first often found dysregulated in BC and the second reported to control stem and mesenchymal cell status in epithelial cells of the mammary gland [56, 57]. The gene discussed is NFATC2; the disease is breast cancer.