LAD1 and breast cancer: Indeed, LAD1 (Ladinin 1) has been proposed as a promising new target for ‘triple negative’ BC treatment [59] and BCL9 (B-cell CLL/lymphoma 9), a co-activator of Wnt-stimulated β-catenin-mediated transcription, is considered a molecular driver of BC early invasion [60] and has been shown to control estrogen signaling and breast carcinogenesis [61].