When interrogating the cbioportal.org repository (www.cBioportal.org– Cerami et al, 2012; Gao et al, 2013), TP53 gene alterations are found in 2.8–10.6% of adult leukaemia and in about 9% of AML cases (Cancer Genome Atlas Research Network, 2013). The gene discussed is TP53; the disease is acute myeloid leukemia.