As illustrated in Figure 4(A,B), the tumor volume of various TRAIL-treated groups was significant lower than control, blank NPs, free Cur and Cur-NPs group (1232.59 ± 70.57 mm3, 1152.13 ± 28.95 mm3, 1016.51 ± 59.91 mm3 and 982.15 ± 48.64 mm3, respectively). The gene discussed is TNFSF10; the disease is neoplasm.