Based on the case history, preliminary tests and CFP alone (round one), the 10 cases were accurately described as AMD by 444/728 responses (61 per cent), rather than normal (41/728, six per cent) or other macular/retinal disease (243/728, 33 per cent), yielding a 94 per cent (687/728) total detection level for the presence of any macular pathology. The gene discussed is CFP; the disease is age-related macular degeneration.