PDZD7 and dementia: For instance, CAMK2G and PDZD7 are involved in Usher Syndrome the most common condition leading to deafness and blindness, as well as DNMT1 has a role in DNMT1-Related Dementia, Deafness, and Sensory Neuropathy (Vernon and Rhodes, 2009) and LRTOMT in deafness.