At 16 h of infection, the IFN repertoire in adult DCs increased both in numbers of genes and in expression strength (IFNA1, IFNA2, IFNA4, IFNA5, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA21, IFNB1, IFNG, and IFNW1), consistent with the observations in cord DCs. This evidence concerns the gene IFNA21 and infection.