A recent study showed that phenanthrene-based tylophorine-1 (PBT-1) binds to hnRNPA2B1 and exerts antitumor activity in part by reducing AKT-mediated lung adenocarcinoma metastasis and tumorigenesis (Chen et al., 2014). Here, HNRNPA2B1 is linked to lung adenocarcinoma.