For instance, in the Icelandic population, SNP haplotype in the 5′ region of NRG1 (HAPICE: SNP8NRG221533, SNP8NRG241930, SNP8NRG243177) was identified with linkage of schizophrenia risk (Stefansson et al., 2002), while in the Scottish population, a significant association between NRG1 (HAPICE) and schizophrenia was detected by PCR (Stefansson et al., 2003). The gene discussed is NRG1; the disease is schizophrenia.