CXCL8 and Alzheimer disease: Microglial expression of C/EBPβ, a protein that regulates pro-inflammatory molecules such as interleukin 6 (IL-6), interleukin 8 (IL-8), granulocyte colony-stimulating factor, tumour necrosis factor alpha (TNF-α), complement C3 and C-reactive protein (CRP), is significantly increased in the AD cortex compared to the non AD cortex4.