Nevertheless, we found that either TGF‐β1 neutralization (Fig 6A) or Tgfbr1 depletion (Fig 6D) in cancer cells significantly abolished Il‐17rb up‐regulation, suggesting a critical role of TGF‐β1 in up‐regulating Il‐17rb expression in cancer cells in the TDLNs. This evidence concerns the gene IL17RB and cancer.