In addition to fabG1 and inhA, we found that 5 other genes fell into this classification: mazF5; mazE5, encoding a toxin-antitoxin module; two tRNAs (leuX and thrU); and ethA. ethA was of particular interest, as it encodes a monooxygenase required for the activation of the prodrug ethionamide (ETH) (22, 23), a key component of treatment of infections cause by MDR strains. This evidence concerns the gene INHA and infection.