IGHG3 and malaria: We explored the hypothesis that the maternal IgG3-H435 variant increased transplacental transfer of anti-malaria IgG3 to the newborn: it was expected that (i) the maternal IgG3-H435 variant would be associated with a better transplacental transfer of IgG3 and (ii) this IgG3 transfer would be equivalent to IgG1 transfer, for which the variant is always IgG1-H435.