This is consistent with a previous study, which describes their upregulation in human oral squamous cell carcinoma in comparison with the normal epithelium,13 but is discordant with observations of reduced ESRP1 and ESRP2 expressions in colorectal cancer tissues.16 Our data provide additional evidence that the expression of these factors is cancer-type-specific. Here, ESRP1 is linked to colorectal cancer.