Most interestingly, a circRNA derived from TCF25 was observed to promote proliferation and migration of bladder cancer cells by sponging miR-103a-3p and miR-107.73 More recently, a circRNA from MYLK was shown to have oncogenic properties in bladder cancer by binding miR-29a and abolishing the endogenous suppressive effect on its target gene VEGFA, in turn, leading to epithelial–mesenchymal transition, angiogenesis and metastasis.53 The gene discussed is TCF25; the disease is urinary bladder carcinoma.