VCAN and glioblastoma: Interestingly, a circRNA derived from the VCAN gene, which is implicated in gliomagenesis, was found to be upregulated in both oligodendroglioma and glioblastoma.83 Barbagallo et al.84 analyzed the expression of miR-671-5p in glioblastoma cell lines and primary patient samples and found it to be overexpressed and correlated with downregulation of ciRS-7.