Despite pre-clinical evidence that resveratrol reduces androgen production and modulates androgen receptor activity, Kjaer et al. concluded that resveratrol could not treat prostate cancer as it had no effect on prostate volume or PSA levels.34 From these studies, it seems unlikely that resveratrol will prove to be an effective treatment for prostate cancer, but more clinical trials need to be performed to confirm this. This evidence concerns the gene KLK3 and Familial prostate cancer.