Further histological assessment using H&E and an immunohistochemical panel staining for myeloid sarcoma [23] which included human CD45, myeloperoxidase (MPO), and CD117 revealed massive infiltration of AML cells into multiple organs and confirmed that the soft tissue mass was myeloid sarcoma composed of AML leukemic blasts (Additional file 3: Figure S3b). This evidence concerns the gene MPO and acute myeloid leukemia.