We also found that GLPG1790 exposure was able to significantly reduce the migratory as well as the clonogenic capacity of RD and TE671 cells by altering the expression of specific proteins, including members of the integrin superfamily, this supporting the role of EPH signalling in regulating the migratory behaviour and metastatic potential of cancer cells [6–8]. This evidence concerns the gene EPHA1 and cancer.