APOB and hyperlipidemia: It has been found previously that eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), the two most important n-3 PUFAs in human physiology, may exert their atheroprotective functions by promoting intracellular catabolism of apolipoprotein B-100 containing lipoproteins, suppressing hepatic apoB production, stimulating plasma triglyceride clearance via lipoprotein lipase (LPL), increasing the very low density lipoprotein (VLDL) to LDL conversion rate, reducing LDL synthesis and attenuating postprandial lipemia [22,23,24,25].