Furthermore, under Hp-WT or Hp-ΔcagA infection, the levels of MAP1LC3B-II in AGS cells transfected with the CagA expression plasmid (GFP-CagA) were decreased in comparison to that in transfected-control cells (Figure 3G), suggesting that over-expression of CagA lead to further reduction of autophagic flux. This evidence concerns the gene MAP1LC3B and infection.