DCXR and glycogen storage disease VI: Compared to other three sample groups, Pi-disease samples had gained specific genes involved in carbohydrate and lipid metabolism (e.g., lacZ, crtB, idi, and glmM), metabolism of cofactors and vitamin (e.g., arfC, UBIG, pncA, and lplA) and amino acid metabolism (e.g., speB, dapE, and E6.4.1.4B) (Figures 4, 5), while Pn-disease samples had extra genes with specific pathways including lipopolysaccharide biosynthesis (e.g., gmhB), pentose and glucuronate intercoversions (e.g., DCXR), and ubiquinone biosynthesis (e.g., menF).