Autoimmune haemolytic anaemia and immune thrombocytopenia have both been reported in IKBKG deficiency, and colitis is a common inflammatory complication.12, 13, 14 Hepatic granuloma have been only been reported in hypofunctional IKBKG due to disseminated mycobacterial infection.13 A liver biopsy performed on P1 found no evidence of mycobacteria or other pathogens, suggesting that the granuloma are sterile and due to immune dysregulation. This evidence concerns the gene IKBKG and autoimmune hemolytic anemia.