P10 (NFKB2 p.R853*) suffered autoimmune alopecia, which is widely reported in patients with dominant negative NFKB2 variants but the renal disease that was present in P10 has not been reported in NKFB2 variants to date.27, 28 The pituitary adrenal axis is often effected in NFKB2, but was normal in P10, although this is not believed to be an AI/I phenomenon; instead due to hypoplasia of the anterior pituitary.27, 28, 29 Further large-scale studies are needed to catalogue the frequencies and phenotype of AI/I in NFKB1 and NFKB2 patients. This evidence concerns the gene NFKB1 and kidney disorder.