Fasting plasma insulin was similar between the T2DM patients and non-diabetic obese/overweight individuals (20.5 ± 2.5 vs. 21.7 ± 3.8 μU/mL) as well as between the lean sedentary individuals and endurance-trained athletes (9.6 ± 1.4 vs. 7.0 ± 0.8 μU/mL) (Table 3). The gene discussed is INS; the disease is type 2 diabetes mellitus.