GOSR2 and epilepsy: In neurons, the impairment of the early anterograde transport might lead to disorders such as epilepsy due to alterations in the regulated release of neurotransmitters, as well as the proper sorting of neurotransmitter receptors at chemical synapses, providing a possible link between mutations in GOSR2 and epilepsy (Giannandrea et al., 2010; Multani et al., 1994).