BECN1 and cystic fibrosis: Microscopy demonstrated that beclin-1 was aggregated into large clumps at baseline (CF beclin-1 mean area 23.8 ± 53.8 pixels vs non-CF 1.5 ± 0.7 pixels) and during B. cenocepacia infection (CF beclin-1 mean area 157.1 ± 916.1 pixels vs non-CF 14.1 ± 25.4 pixels) in CF compared to non-CF MDMs (Fig 6A).