However, a recent review from the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project noted that sTfR levels may be affected by inflammation via alternative mechanisms, such as iron-limited erythropoiesis and hypoxemia [16], and others have observed sTfR elevation with asymptomatic malaria [17]. The gene discussed is TFRC; the disease is anemia (phenotype).