As a result of these observations and our previous finding that Survivin, IAPs, and HSP70 are packaged in EVs and could be implicated as plausible biomarkers for PCa progression [15, 16, 23, 24], we hypothesized that Survivin and other stress survival proteins could be released differentially in AA and EA patients with PCa. The gene discussed is BIRC5; the disease is posterior cortical atrophy.