To test this, we used a previously reported HCMV mutant virus that encodes an inactive DUB.19 After infecting HFFs with equal amount of WT and DUB-mutant (ΔDUB) GFP-tagged HCMV, an equal amount of virus infection (GFP Fluorescence) was observed on second dpi (Figure 2a). The gene discussed is ZUP1; the disease is viral infectious disease.