TP53 and colorectal carcinoma: Autophagy can be regulated by p53-associated non-coding RNAs (for example, miR34a, miR-218 and miR-502).65, 70, 71, 72 In this study, we found that BA treatment induced miR-218 expression in three CRC cells, whereas it significantly enhanced miR-502 expression in HCT116 and HT29 cells and slightly augmented it in SW480 cells (Supplementary Figure S15).