HOTAIR promotes lung cancer cell migration and invasion by interacting with chromatin remodeling factor LSH to influence the ratio of FOXA1 to FOXA2.30 NEAT1 promotes NSCLC progression by functioning as a competing endogenous RNA (ceRNA) for hsa-miR-377-3p.31 Our previous study showed that lncRNA, LINC00152, contributes to NSCLC cell proliferation though suppression of IL24 expression, which is mediated by interaction with EZH2.29 However, the contribution of other dysregulated lncRNAs to NSCLC, and their functions and molecular mechanisms in NSCLC cells are poorly understood. This evidence concerns the gene HOTAIR and lung carcinoma.