EMT has been shown to be associated with the progress of cancer, the metastatic spread and progression of cells from the site of the primary tumor to the surrounding tissues and distant organs.6, 7, 8 TS has been documented to promote EMT.9, 10, 11 TS-induced EMT has been found to regulate early events in cancer progression such as downregulation of epithelial cadherin, loss of cell junctions and apical–basal polarity, and enabling cells motility.11 However, the underlying mechanisms regarding how TS induces EMT and the signaling events involved remains poorly understood. The gene discussed is CDH1; the disease is cancer.