(A) Co-immunofluorescent staining for CK19 (green), Amylase (red), SMA (magenta) and DAPI (blue); (B) co-immunofluorescent staining for Cleaved caspase 3 (green), E-cadherin (magenta) and DAPI (blue); (C) co-immunofluorescent staining for p-ERK1/2 (green), CK19 (red), SMA (magenta) and DAPI (blue) in iKras* and iKras*;CD11b-DTR pancreata 3 weeks post pancreatitis and 3 days, 1 week upon Kras* inactivation and DT treatment. The gene discussed is SMN1; the disease is pancreatitis.