(A) Periodic acid–Schiff (PAS) staining; (B) immunohistochemistry staining for Cleaved caspase three and (C) F4/80 in iKras* and iKras*;CD11b-DTR pancreata 3 week post pancreatitis induction and in iKras*;CD11b-DTR pancreata following DT treatment for 3 days and 1 week. The gene discussed is ITGAM; the disease is pancreatitis.