Twelve differential proteins identified before tumor mass appearance on day 4 were also differentially expressed at later time points, including Galectin‐3‐binding protein, Complement C4, Beta‐2‐microglobulin, Haptoglobin, Macrophage colony‐stimulating factor 1, Coagulation factor XII and Apolipoprotein A‐IV. Here, F12 is linked to neoplasm.