ESR1 and neoplasm: We used unadjusted Cox regression and observed that race (White vs. African American), age (≤60 years vs. >60 years), Charlson score (1 or 2 vs. 0), T‐stage, tumor grade(III vs. I), ER/PR/HER2 status, lung metastasis (Yes vs. No), liver metastasis (Yes vs. No), brain metastasis (Yes vs. No), breast surgery(BCS/Mastectomy vs. No), radiation therapy (Yes vs. No), and chemotherapy (Multiagent vs. None) were significantly associated with OS.