ALB and intracranial hemorrhage: - pregnancy and breastfeeding;- perinatal period and early infancy;- acute liver failure;-moderate-severe renal failure (particularly when anuria/oligouria);-dialysis treatment in the presence of severe abnormalities of haemostasis and baseline albumin < 2 – 2.5 g/dL;- intracranial haemorrhage;- Hypersensitivity.