According to another study performed over 135 patients in an academic hospital in Tehran, albumin had been used mostly in volume expansion after the heart surgery (53.3%), nutrition source in malnourished patients (19.3%), paracentesis (12.9%), plasmapheresis (9.6%), hypoalbuminemia (3%) and the others (2.1%). The gene discussed is ALB; the disease is Hypoalbuminemia.