Rs894278 and rs11931074 SNPs in SNCA has been identified as conferring the strongest PD risk (Liu et al., 2013) and recently, studies have shown these two SNPs were also associated with some other phenotypes in PD, such as festination (Zheng et al., 2017) and earlier onset of PD (Huang et al., 2015). This evidence concerns the gene SNCA and Parkinson disease.