Several studies have reported the detection of fusion genes in SCC of other organs (AML4-ALK in lung SCC, FGFR3-TACC3 in head and neck SCC, NSD3-NUT in NUT midline carcinoma, and GOLM1-MAK10 in esophageal SCC). Here, TACC3 is linked to esophageal squamous cell carcinoma.